DOI for 'CMIP6.ScenarioMIP.IPSL.IPSL-CM6A-LR'

IsSourceOf  ISIMIP3b bias-adjusted atmospheric climate input data. Lange, Stefan; Büchner, Matthias. DOI:10.48364/isimip.842396.1

IsSourceOf  ISIMIP3b bias-adjusted atmospheric climate input data. Lange, Stefan; Büchner, Matthias. DOI:10.48364/isimip.842396

IsSourceOf  ISIMIP3b ocean input data. Büchner, Matthias. DOI:10.48364/isimip.575744

IsReferencedBy  Evaluating stratospheric ozone and water vapour changes in CMIP6 models from 1850 to 2100. Keeble, James; Chiodo, Gabriel; Et Al.. DOI:10.3929/ethz-b-000478110

IsReferencedBy  Twenty-first century ocean warming, acidification, deoxygenation, and upper-ocean nutrient and primary production decline from CMIP6 model projections. Kwiatkowski, Lester; Torres, Olivier; Bopp, Laurent; Aumont, Olivier; Chamberlain, Matthew; Christian, James R.; Dunne, John P.; Gehlen, Marion; Ilyina, Tatiana; John, Jasmin G.; Lenton, Andrew; Li, Hongmei; Lovenduski, Nicole S.; Orr, James C.; Palmieri, Julien; Santana-Falcón, Yeray; Schwinger, Jörg; Séférian, Roland; Stock, Charles A.; Tagliabue, Alessandro; Takano, Yohei; Tjiputra, Jerry; Toyama, Katsuya; Tsujino, Hiroyuki; Watanabe, Michio; Yamamoto, Akitomo; Yool, Andrew; Ziehn, Tilo. DOI:10.5194/bg-17-3439-2020

IsReferencedBy  Arctic Ocean acidification over the 21st century co-driven by anthropogenic carbon increases and freshening in the CMIP6 model ensemble. Terhaar, Jens; Torres, Olivier; Bourgeois, Timothée; Kwiatkowski, Lester. DOI:10.5194/egusphere-egu21-7937

IsSourceOf  Secondary ISIMIP3b bias-adjusted atmospheric climate input data. Lange, Stefan; Büchner, Matthias. DOI:10.48364/isimip.581124.1

IsSourceOf  ISIMIP3b ocean input data. Büchner, Matthias. DOI:10.48364/isimip.575744.2

IsReferencedBy  Evaluating stratospheric ozone and water vapour changes in CMIP6 models from 1850 to 2100. Keeble, James; Hassler, Birgit; Banerjee, Antara; Checa-Garcia, Ramiro; Chiodo, Gabriel; Davis, Sean; Eyring, Veronika; Griffiths, Paul T.; Morgenstern, Olaf; Nowack, Peer; Zeng, Guang; Zhang, Jiankai; Bodeker, Greg; Burrows, Susannah; Cameron-Smith, Philip; Cugnet, David; Danek, Christopher; Deushi, Makoto; Horowitz, Larry W.; Kubin, Anne; Li, Lijuan; Lohmann, Gerrit; Michou, Martine; Mills, Michael J.; Nabat, Pierre; Olivié, Dirk; Park, Sungsu; Seland, Øyvind; Stoll, Jens; Wieners, Karl-Hermann; Wu, Tongwen. DOI:10.5194/acp-21-5015-2021

IsSourceOf  Secondary ISIMIP3b bias-adjusted atmospheric climate input data. Lange, Stefan; Büchner, Matthias. DOI:10.48364/isimip.581124

IsCitedBy  Ocean, Cryosphere and Sea Level Change. In Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Fox-Kemper, B.; Hewitt, H.T.; Xiao, C.; Aðalgeirsdóttir, G.; Drijfhout, S.S.; Edwards, T.L.; Golledge, N.R.; Hemer, M.; Kopp, R.E.; Krinner, G.; Mix, A.; Notz, D.; Nowicki, S.; Nurhati, I.S.; Ruiz, L.; Sallée, J.-B.; Slangen, A.B.A.; Yu, Y.. DOI:10.1017/9781009157896.011

IsSourceOf  ISIMIP3b ocean input data. Büchner, Matthias. DOI:10.48364/isimip.575744.1

IsCitedBy  Future Global Climate: Scenario-Based Projections and Near-Term Information. In Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Lee, J.-Y.; Marotzke, J.; Bala, G.; Cao, L.; Corti, S.; Dunne, J.P.; Engelbrecht, F.; Fischer, E.; Fyfe, J.C; Jones, C.; Maycock, A.; Mutemi, J.; Ndiaye, O.; Panickal, S.; Zhou,T.. DOI:10.1017/9781009157896.006

IsCitedBy  Human Influence on the Climate System. In Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Eyring, V.; Gillett, N.P.; Achuta Rao, K.M.; Barimalala, R.; Barreiro Parrillo, M.; Bellouin, N.; Cassou, C.; Durack, P.J.; Kosaka, Y.; McGregor, S.; Min, S.; Morgenstern, O.; Sun, Y.. DOI:10.1017/9781009157896.005

IsCitedBy  Linking Global to Regional Climate Change. In Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Doblas-Reyes, F.J.; Sörensson, A.A.; Almazroui, M.; Dosio, A.; Gutowski, W.J.; Haarsma, R.; Hamdi, R.; Hewitson, B.; Kwon, W.-T.; Lamptey, B.L.; Maraun, D.; Stephenson, T.S.; Takayabu, I.; Terray, L.; Turner, A.; Zuo, Z.. DOI:10.1017/9781009157896.012

IsCitedBy  Weather and Climate Extreme Events in a Changing Climate. In Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Seneviratne, S.I.; Zhang, X.; Adnan, M.; Badi, W.; Dereczynski, C.; Di Luca, A.; Ghosh, S.; Iskandar, I.; Kossin, J.; Lewis, S.; Otto, F.; Pinto, I.; Satoh, M.; Vicente-Serrano, S.M.; Wehner, M.; Zhou, B.. DOI:10.1017/9781009157896.013

IsCitedBy  Atlas. In Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Gutiérrez, J.M.; Jones, R.G.; Narisma, G.T.; Alves, L.M.; Amjad, M.; Gorodetskaya, I.V.; Grose, M.; Klutse, N.A.B.; Krakovska, S.; Li, J.; Martínez-Castro, D.; Mearns, L.O.; Mernild, S.H.; Ngo-Duc, T.; van den Hurk, B.; Yoon, J.-H.. DOI:10.1017/9781009157896.021

IsCitedBy  Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Intergovernmental Panel on Climate Change (IPCC). DOI:10.1017/9781009157896

IsReferencedBy  Stringent mitigation substantially reduces risk of unprecedented near-term warming rates. McKenna, Christine M.; Maycock, Amanda C.; Forster, Piers M.; Smith, Christopher J.; Tokarska, Katarzyna B.. DOI:10.1038/s41558-020-00957-9

IsReferencedBy  Evaluating the Ozone Valley over the Tibetan Plateau in CMIP6 Models. Zhang, Kequan; Duan, Jiakang; Zhao, Siyi; Zhang, Jiankai; Keeble, James; Liu, Hongwen. DOI:10.1007/s00376-021-0442-2

IsReferencedBy  Effects of Surface Ozone and Climate on Historical (1980–2015) Crop Yields in the United States: Implication for Mid-21st Century Projection. Da, Yabin; Xu, Yangyang; McCarl, Bruce. DOI:10.1007/s10640-021-00629-y

IsReferencedBy  Climate change in the High Mountain Asia in CMIP6. Lalande, Mickaël; Ménégoz, Martin; Krinner, Gerhard; Naegeli, Kathrin; Wunderle, Stefan. DOI:10.5194/esd-2021-43

IsReferencedBy  Diazotrophy as a key driver of the response of marine net primary productivity to climate change. Bopp, Laurent; Aumont, Olivier; Kwiatkowski, Lester; Clerc, Corentin; Dupont, Léonard; Ethé, Christian; Gorgues, Thomas; Séférian, Roland; Tagliabue, Alessandro. DOI:10.5194/bg-19-4267-2022

IsReferencedBy  Warming-induced vegetation growth cancels out soil carbon-climate feedback in the northern Asian permafrost region in the 21st century. Liu, Jianzhao; Yuan, Fenghui; Zuo, Yunjiang; Zhou, Rui; Zhu, Xinhao; Li, Kexin; Wang, Nannan; Chen, Ning; Guo, Ziyu; Zhang, Lihua; Sun, Ying; Guo, Yuedong; Song, Changchun; Xu, Xiaofeng. DOI:10.1088/1748-9326/ac7eda

IsReferencedBy  Atmospheric Circulation Constraints on 21st Century Seasonal Precipitation Storylines for the Southwestern United States. Grise, Kevin M.. DOI:10.1029/2022gl099443

IsRelatedTo  ISIMIP3b ocean input data. Büchner, Matthias. DOI:10.48364/isimip.575744.3

IsRelatedTo  Evaluating stratospheric ozone and water vapor changes in CMIP6 models from 1850–2100. Keeble, James; Hassler, Birgit; Banerjee, Antara; Checa-Garcia, Ramiro; Chiodo, Gabriel; Davis, Sean; Eyring, Veronika; Griffiths, Paul T.; Morgenstern, Olaf; Nowack, Peer; Zeng, Guang; Zhang, Jiankai; Bodeker, Greg; Cugnet, David; Danabasoglu, Gokhan; Deushi, Makoto; Horowitz, Larry W.; Li, Lijuan; Michou, Martine; Mills, Michael J.; Nabat, Pierre; Park, Sungsu; Wu, Tongwen. DOI:10.5194/acp-2019-1202

IsReferencedBy  Increases in Future AR Count and Size: Overview of the ARTMIP Tier 2 CMIP5/6 Experiment. O'Brien, Travis Allen; Wehner, Michael F; Payne, Ashley E.; Shields, Christine A; Rutz, Jonathan J.; Leung, L. Ruby; Ralph, F. Martin; Marquardt Collow, Allison B.; Gorodetskaya, Irina; Guan, Bin; Lora, Juan Manuel; McClenny, Elizabeth; Nardi, Kyle M.; Ramos, Alexandre M.; Tomé, Ricardo; Sarangi, Chandan; Shearer, Eric Jay; Ullrich, Paul; Zarzycki, Colin M.; Loring, Burlen; Huang, Huanping; Inda Díaz, Héctor Alejandro; Rhoades, Alan M.; Zhou, Yang. DOI:10.1002/essoar.10504170.2

IsReferencedBy  Predicting the Effects of Climate Change on Dengue Vector Densities in Southeast Asia through Process-Based Modeling. Bonnin, Lucas; Tran, Annelise; Herbreteau, Vincent; Marcombe, Sébastien; Boyer, Sébastien; Mangeas, Morgan; Menkes, Christophe. DOI:10.1289/ehp11068

IsCitedBy  Global Carbon and other Biogeochemical Cycles and Feedbacks. In Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Canadell, J.G.; Monteiro, P.M.S; Costa, M.H.; Cotrim da Cunha, L.; Cox, P.M.; Eliseev, A.V.; Henson, S.; Ishii, M.; Jaccard, S.; Koven, C.; Lohila, A.; Patra, P.K.; Piao, S.; Rogelj, J.; Syampungani, S.; Zaehle, S.; Zickfeld, K.. DOI:10.1017/9781009157896.007

IsCitedBy  Water Cycle Changes. In Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J.B.R. Matthews, T.K. Maycock, T. Waterfield, O. Yelekçi, R. Yu, and B. Zhou (eds.)]. Douville, H.; Raghavan, K.; Renwick, J.; Allan, R.P.; Arias, P.A.; Barlow, M.; Cerezo-Mota, R.; Cherchi, A.; Gan, T.Y.; Gergis, J.; Jiang, D.; Khan, A.; Pokam Mba, W.; Rosenfeld, D.; Tierney, J.; Zolina, O.. DOI:10.1017/9781009157896.010

IsRelatedTo  Secondary ISIMIP3b bias-adjusted atmospheric climate input data. Lange, Stefan; Quesada-Chacón, Dánnell; Büchner, Matthias. DOI:10.48364/isimip.581124.2

IsReferencedBy  Arctic Ocean acidification over the 21st century co-driven by anthropogenic carbon increases and freshening in the CMIP6 model ensemble. Terhaar, Jens; Torres, Olivier; Bourgeois, Timothée; Kwiatkowski, Lester. DOI:10.5194/bg-18-2221-2021

IsReferencedBy  Climate change projections in Guatemala: temperature and precipitation changes according to CMIP6 models. Rivera, Paris. DOI:10.1007/s40808-023-01881-5

IsReferencedBy  Robust global detection of forced changes in mean and extreme precipitation despite observational disagreement on the magnitude of change. de Vries, Iris Elisabeth; Sippel, Sebastian; Pendergrass, Angeline Greene; Knutti, Reto. DOI:10.5194/esd-14-81-2023

IsReferencedBy  Arctic Ocean acidification over the 21st century co-driven by anthropogenic carbon increases and freshening in the CMIP6 model ensemble. Terhaar, Jens; Torres, Olivier; Bourgeois, Timothée; Kwiatkowski, Lester. DOI:10.5194/bg-2020-456

IsReferencedBy  Probabilistic projections of El Niño Southern Oscillation properties accounting for model dependence and skill. Olson, Roman; Kim, Soong-Ki; Fan, Yanan; An, Soon-Il. DOI:10.1038/s41598-022-26513-3

IsRelatedTo  Variability in Projected North American Mean and Extreme Temperature and Precipitation Trends for the 21st Century: Model‐To‐Model Differences Versus Internal Variability. Kelleher, Mitchell K.; Grise, Kevin M.; Schmidt, Daniel F.. DOI:10.1029/2022ef003161

IsReferencedBy  Prediction of Native Seed Habitat Distribution According to SSP Scenario and Seed Transfer Zones: A Focus on Acer pictum subsp. mono and Quercus acuta. Kim, Chaeyoung; Kim, Wheemoon; Song, Wonkyong; Cho, Jaepil; Choi, Jaeyong. DOI:10.3390/f14010087

IsReferencedBy  Comment on egusphere-2022-971. Wagner, Wolfgang. DOI:10.5194/egusphere-2022-971-rc2

IsReferencedBy  Root zone soil moisture in over 25 % of global land permanently beyond pre-industrial variability as early as 2050. Lai, En Ning; Wang-Erlandsson, Lan; Virkki, Vili; Porkka, Miina; van der Ent, Ruud J.. DOI:10.5194/egusphere-2022-971

IsReferencedBy  Global peatlands under future climate – seamless model projections from the Last Glacial Maximum. Müller, Jurek; Joos, Fortunat. DOI:10.5194/bg-2021-80

IsReferencedBy  Predicting the Habitat Suitability for Angelica gigas Medicinal Herb Using an Ensemble Species Distribution Model. Jung, Jong Bin; Park, Go Eun; Kim, Hyun Jun; Huh, Jeong Hoon; Um, Yurry. DOI:10.3390/f14030592

IsReferencedBy  Stochastic Spatial Binary Simulation with Multivariate Normal Distribution for Illustrating Future Evolution of Umbrella-Shape Summer Shelter under Climate Change. Lee, Taesam; Choi, Younghwan; Singh, Vijay P.. DOI:10.3390/su15043147

IsReferencedBy  Global and northern-high-latitude net ecosystem production in the 21st century from CMIP6 experiments. Qiu, Han; Hao, Dalei; Zeng, Yelu; Zhang, Xuesong; Chen, Min. DOI:10.5194/esd-14-1-2023

IsReferencedBy  Review of bg-2021-80. Kleinen, Thomas. DOI:10.5194/bg-2021-80-rc2

IsReferencedBy  Adapting to the projected epidemics of Fusarium head blight of wheat in Korea under climate change scenarios. Jung, Jin-Yong; Kim, Jin-Hee; Baek, Minju; Cho, Chuloh; Cho, Jaepil; Kim, Junhwan; Pavan, Willingthon; Kim, Kwang-Hyung. DOI:10.3389/fpls.2022.1040752

IsRelatedTo  Current-climate sea ice amount and seasonality as constraints for future Arctic amplification. Linke, Olivia; Feldl, Nicole; Quaas, Johannes. DOI:10.1088/2752-5295/acf4b7

IsRelatedTo  Climate change in the High Mountain Asia in CMIP6. Lalande, Mickaël; Ménégoz, Martin; Krinner, Gerhard; Naegeli, Kathrin; Wunderle, Stefan. DOI:10.5194/esd-12-1061-2021

IsReferencedBy  Committed and projected future changes in global peatlands – continued transient model simulations since the Last Glacial Maximum. Müller, Jurek; Joos, Fortunat. DOI:10.5194/bg-18-3657-2021

IsReferencedBy  Response to reviewer comments. Müller, Jurek. DOI:10.5194/bg-2020-110-ac1

IsReferencedBy  Reply on RC3. van der Ent, Ruud. DOI:10.5194/egusphere-2022-971-ac3

IsReferencedBy  Reply on RC2. van der Ent, Ruud. DOI:10.5194/egusphere-2022-971-ac2

IsReferencedBy  Reply on RC1. van der Ent, Ruud. DOI:10.5194/egusphere-2022-971-ac1

IsReferencedBy  High-resolution CMIP6 climate projections for Ethiopia using the gridded statistical downscaling method. Rettie, Fasil M.; Gayler, Sebastian; Weber, Tobias K. D.; Tesfaye, Kindie; Streck, Thilo. DOI:10.1038/s41597-023-02337-2

IsReferencedBy  Total ozone content, total cloud cover, and aerosol optical depth in CMIP6: simulations performance and projected changes. Yamamoto, Ana Letícia Campos; Corrêa, Marcelo de Paula; Torres, Roger Rodrigues; Martins, Fabrina Bolzan; Godin-Beekmann, Sophie. DOI:10.1007/s00704-023-04821-6

IsReferencedBy  Temporal downscaling of daily precipitation to 10 min data for assessment of climate change impact on floods in small-size watersheds applied to Jinju, South Korea. Lee, Taesam; Jo, Jaephil; Singh, Vijay P.. DOI:10.1007/s00382-022-06216-1

IsReferencedBy  Uncertainties, limits, and benefits of climate change mitigation for soil moisture drought in southwestern North America. Cook, B. I.; Mankin, J. S.; Williams, A. P.; Marvel, K. D.; Smerdon, J. E.; Liu, H.. DOI:10.1029/2021EF002014

IsRelatedTo  Quantifying climate change impacts on hydropower production under CMIP6 multi-model ensemble projections using SWAT model. Yalcin, Emrah. DOI:10.1080/02626667.2023.2245815

IsReferencedBy  Uncertainties, Limits, and Benefits of Climate Change Mitigation for Soil Moisture Drought in Southwestern North America. Cook, B. I.; Mankin, J. S.; Williams, A. P.; Marvel, K. D.; Smerdon, J. E.; Liu, H.. DOI:10.1029/2021ef002014

IsRelatedTo  Projected changes in early summer ridging and drought over the Central Plains. Cook, Benjamin I; Williams, A Park; Marvel, Kate. DOI:10.1088/1748-9326/ac8e1a

IsReferencedBy  First Application of Artificial Neural Networks to Estimate 21st Century Greenland Ice Sheet Surface Melt. Sellevold, Raymond; Vizcaino, Miren. DOI:10.1029/2021gl092449

IsReferencedBy  Twenty-first century ocean warming, acidification, deoxygenation, and upper ocean nutrient decline from CMIP6 model projections. Kwiatkowski, Lester; Torres, Olivier; Bopp, Laurent; Aumont, Olivier; Chamberlain, Matthew; Christian, James; Dunne, John P.; Gehlen, Marion; Ilyina, Tatiana; John, Jasmin G.; Lenton, Andrew; Li, Hongmei; Lovenduski, Nicole S.; Orr, James C.; Palmieri, Julien; Schwinger, Jörg; Séférian, Roland; Stock, Charles A.; Tagliabue, Alessandro; Takano, Yohei; Tjiputra, Jerry; Toyama, Katsuya; Tsujino, Hiroyuki; Watanabe, Michio; Yamamoto, Akitomo; Yool, Andrew; Ziehn, Tilo. DOI:10.5194/bg-2020-16

IsReferencedBy  Historical and Projected Trends of the Mean Surface Temperature in South-Southeast Mexico Using ERA5 and CMIP6. Andrade-Velázquez, Mercedes; Montero-Martínez, Martín José. DOI:10.3390/cli11050111